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Current Concepts in Cardiac CT Angiography for Patients With Acute Chest Pain
Seung Min Yoo1, Ji Young Rho, Hwa Yeon Lee
1Department of Diagnostic Radiology, CHA Medical University Hospital, Seongnam, Korea.
Insights
Delayed diagnosis of acute coronary syndrome, aortic dissection, and pulmonary embolism can be avoided by using cardiac CT angiography (CTA) to triage patients with chest pain. This approach improves diagnostic accuracy and safety.
Area of Science:
- Cardiovascular Imaging
- Emergency Medicine
- Radiology
Background:
- Nonspecific acute chest pain is a common emergency department presentation.
- Delayed diagnosis of critical conditions like acute coronary syndrome, aortic dissection, and pulmonary embolism can occur.
- Current triage strategies may not always be optimal.
Purpose of the Study:
- To present specific examples of delayed diagnoses due to suboptimal triage of acute chest pain.
- To advocate for the use of cardiac CT angiography (CTA) in triaging patients with nonspecific acute chest pain.
- To provide guidance on selecting appropriate CTA protocols and interpreting results.
Main Methods:
- Review of clinical cases with delayed diagnoses of acute coronary syndrome, aortic dissection, and pulmonary embolism.
- Discussion of the utility of dedicated coronary CTA versus triple rule-out (TRO) CTA for triage.
- Analysis of factors influencing the choice between dedicated coronary CTA, TRO CTA, and dedicated pulmonary or aortic CTA.
- Evaluation of biphasic versus triphasic contrast administration in TRO examinations.
Main Results:
- Specific examples illustrate how immediate dedicated coronary CTA or TRO CTA could have prevented delayed diagnoses.
- Choosing the correct CTA protocol based on clinical context is crucial for accurate diagnosis.
- Understanding CTA interpretation and contrast administration techniques enhances diagnostic performance.
Conclusions:
- Cardiac CTA, including dedicated coronary CTA and TRO protocols, is valuable for triaging patients with acute chest pain.
- Appropriate selection and interpretation of CTA protocols improve diagnostic accuracy.
- Optimized CTA protocols minimize radiation exposure and contrast-related risks.
Abstract:
This article presents specific examples of delayed diagnosis of acute coronary syndrome, acute aortic dissection, and pulmonary embolism resulting from evaluating patients with nonspecific acute chest pain who did not undergo immediate dedicated coronary CT angiography (CTA) or triple rule-out protocol (TRO). These concrete examples of delayed diagnosis may advance the concept of using cardiac CTA (i.e., dedicated coronary CTA versus TRO) to triage patients with nonspecific acute chest pain. This article also provides an overall understanding of how to choose the most appropriate examination based on the specific clinical situation in the emergency department (i.e., dedicated coronary CTA versus TRO versus dedicated pulmonary or aortic CTA), how to interpret the CTA results, and the pros and cons of biphasic versus triphasic administration of intravenous contrast material during TRO examination. A precise understanding of various cardiac CTA protocols will improve the diagnostic performance of radiologists while minimizing hazards related to radiation exposure and contrast use.
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