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Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
04:40

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans

Published on: August 28, 2018

Comparison of Plaque Composition in Diabetic and Non-Diabetic Patients With Coronary Artery Disease Using Multislice

Yong-Seop Kwon1, Jae-Sik Jang, Chang-Won Lee

  • 1Department of Internal Medicine, Busan St. Mary's Hospital, Busan, Korea.

Korean Circulation Journal
|January 11, 2011
PubMed

Insights

Diabetic patients show a higher degree of mixed coronary plaque burden compared to non-diabetic individuals. Multislice computed tomography angiography can noninvasively assess these differences in plaque composition.

Area of Science:

  • Cardiovascular Imaging
  • Diabetology
  • Interventional Cardiology

Background:

  • Coronary plaque composition, not just luminal narrowing, may predict cardiovascular events in high-risk patients.
  • Diabetes mellitus is a significant risk factor for coronary artery disease (CAD).

Purpose of the Study:

  • To compare plaque burden and composition using multislice computed tomography (MSCT) angiography in diabetic versus non-diabetic patients.
  • To evaluate the utility of MSCT angiography in assessing coronary plaque characteristics.

Main Methods:

  • 452 patients underwent MSCT angiography; 92 with invasive coronary angiography were analyzed.
  • Coronary plaque presence, type, and luminal narrowing severity were assessed.
  • MSCT angiography performance was compared to conventional coronary angiography.

Main Results:

  • Diabetic patients had a higher prevalence of mixed coronary plaque compared to non-diabetic patients.
  • MSCT angiography demonstrated high accuracy (AUC 0.88) in predicting significant coronary artery disease.
  • No significant difference was observed in the proportion of patients with multiple plaque types (p=0.485).

Conclusions:

  • MSCT angiography can noninvasively differentiate coronary plaque composition between diabetic and non-diabetic patients.
  • Mixed plaque types contribute more significantly to the total plaque burden in diabetic patients.
Abstract

Keywords:
Coronary artery diseasesDiabetes

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