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Fatal necrotizing fasciitis due to Streptococcus pneumoniae: a case report
So-Youn Park1, So Young Park, Soo-Youn Moon
1Division of Infectious Diseases, Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea.
Abstract:
Necrotizing fasciitis is known to be a highly lethal infection of deep-seated subcutaneous tissue and superficial fascia. Reports of necrotizing fasciitis due to Streptococcus pneumoniae are exceedingly rare. We report a case of necrotizing fasciitis in a 62-yr-old man with liver cirrhosis and diabetes mellitus. He presented with painful swelling of left leg and right hand. On the day of admission, compartment syndrome was aggravated and the patient underwent surgical exploration. Intra-operative findings revealed necrotizing fasciitis and cultures of two blood samples and wound aspirates showed S. pneumoniae. The patient died despite debridement and proper antimicrobial treatment. To the best of our knowledge, this is the first case of fatal necrotizing fasciitis with meningitis reported in Korea. We also review and discuss the literature on pneumococcal necrotizing fasciitis.
Insights
Necrotizing fasciitis caused by Streptococcus pneumoniae is rare and often fatal. This case highlights a fatal instance in a patient with cirrhosis and diabetes, emphasizing the need for awareness of this severe infection.
Area of Science:
- Infectious Diseases
- Microbiology
- Surgical Pathology
Background:
- Necrotizing fasciitis is a severe, rapidly progressing infection affecting deep subcutaneous tissues and fascia.
- Infections caused by Streptococcus pneumoniae leading to necrotizing fasciitis are exceptionally rare in medical literature.
- Comorbidities like liver cirrhosis and diabetes mellitus can increase susceptibility to severe infections.
Observation:
- A 62-year-old male with liver cirrhosis and diabetes presented with acute leg and hand swelling.
- Compartment syndrome rapidly progressed, necessitating surgical intervention.
- Intraoperative findings confirmed necrotizing fasciitis.
Findings:
- Blood and wound cultures identified Streptococcus pneumoniae as the causative agent.
- The patient succumbed to the infection despite aggressive surgical debridement and antimicrobial therapy.
- This case represents the first reported instance of fatal pneumococcal necrotizing fasciitis with meningitis in Korea.
Implications:
- Streptococcus pneumoniae should be considered in the differential diagnosis of necrotizing fasciitis, especially in immunocompromised patients.
- Early recognition and aggressive management are critical for improving outcomes in necrotizing fasciitis.
- Further research into pneumococcal necrotizing fasciitis pathogenesis and treatment is warranted.
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