Fatal necrotizing fasciitis due to Streptococcus pneumoniae: a case report

So-Youn Park1, So Young Park, Soo-Youn Moon

  • 1Division of Infectious Diseases, Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea.

Insights

Necrotizing fasciitis caused by Streptococcus pneumoniae is rare and often fatal. This case highlights a fatal instance in a patient with cirrhosis and diabetes, emphasizing the need for awareness of this severe infection.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Surgical Pathology

Background:

  • Necrotizing fasciitis is a severe, rapidly progressing infection affecting deep subcutaneous tissues and fascia.
  • Infections caused by Streptococcus pneumoniae leading to necrotizing fasciitis are exceptionally rare in medical literature.
  • Comorbidities like liver cirrhosis and diabetes mellitus can increase susceptibility to severe infections.

Observation:

  • A 62-year-old male with liver cirrhosis and diabetes presented with acute leg and hand swelling.
  • Compartment syndrome rapidly progressed, necessitating surgical intervention.
  • Intraoperative findings confirmed necrotizing fasciitis.

Findings:

  • Blood and wound cultures identified Streptococcus pneumoniae as the causative agent.
  • The patient succumbed to the infection despite aggressive surgical debridement and antimicrobial therapy.
  • This case represents the first reported instance of fatal pneumococcal necrotizing fasciitis with meningitis in Korea.

Implications:

  • Streptococcus pneumoniae should be considered in the differential diagnosis of necrotizing fasciitis, especially in immunocompromised patients.
  • Early recognition and aggressive management are critical for improving outcomes in necrotizing fasciitis.
  • Further research into pneumococcal necrotizing fasciitis pathogenesis and treatment is warranted.

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