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Spectrophotometric Assay of Mefenamic Acid in Tablets Using 1,4-dioxane as Solvent for Extraction
G Mathai1, J T Moolayil, K B Jose
1Department of Chemistry, Sacred Heart College, Thevara, Kochi- 682 013, India.
Indian Journal of Pharmaceutical Sciences
|January 11, 2011
Abstract:
A spectrophotometric method of assay of mefenamic acid in tablets involving, dissolving the tablet powder in 1,4-dioxane and measuring the absorbance at 353.2 nm. The concentration of mefenamic acid is determined using the previously prepared calibration curve using standard solution of mefenamic acid in dioxane. The method was tested by assay of six different commercial tablets containing mefenamic acid.
