[Evidence Based Medicine: shadows and lights]

When taking decisions as regards patient care, based on the evidence (MBE) medicine is the conscious, wise and explicit utilization of the best available tests. The utilization of this strategy involves the recognition of the patches in the knowledge, the realization of a precise research in primary information sources, the analysis of the validity of the discoveries and their utilization in problem solving. The MBE has emerged in a frame of explosion regarding clinical research and access to the information. It has also been a response to the difficulty of keeping up-dated, to the increasing variability in the clinical practice, and to the non-application of measures with checked security and effectiveness. However, it is worrying the fact that a great part of the investigation tests are designed, conducted and analyzed by the pharmaceutical industry. This phenomenon has introduced a worrying distortion because it investigates what it is interesting for the pharmaceutical companies. On the other hand, financial sources mainly achieve results which are favourable to their interests, which are more spread and communicated through different mechanisms.