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Adherence, invasion, toxigenic, and chemotactic properties of Mexican campylobacter strains

Ismael Malagón1, Santos García, Norma Heredia

  • 1Departamento de Microbiología e Inmunología, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, Ciudad Universitaria, San Nicolás de los Garza, N.L. 66451, México.

Journal of Food Protection
|January 12, 2011
PubMed

Insights

Mexican Campylobacter strains possess virulence factors like toxin production, motility, and cell invasion. These factors, found in food and human isolates, pose significant public health risks in Mexico.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Food Safety

Background:

  • Campylobacter jejuni and Campylobacter coli are leading causes of bacterial gastroenteritis globally.
  • Understanding the virulence factors of wild-type strains is crucial for assessing public health risks.

Purpose of the Study:

  • To characterize the virulence factors of Mexican wild-type strains of Campylobacter jejuni and Campylobacter coli.
  • To evaluate their potential impact on public health.

Main Methods:

  • Isolation of 31 wild-type strains from food and human sources in Mexico.
  • Assay of cytolethal distending toxin production, adherence, and invasion in Vero cells.
  • Chemotaxis, motility, and hemolytic activity analyses using specific agar media.

Main Results:

  • All tested strains exhibited hemolytic activity and cytotoxicity in Vero cells.
  • Motility was observed in 9 C. jejuni and 8 C. coli strains.
  • Strains demonstrated varying degrees of adherence and invasion, with C. jejuni showing stronger adherence but less invasion than C. coli (non-significant difference).

Conclusions:

  • Mexican wild-type Campylobacter strains possess key virulence factors.
  • These bacteria, found in food and human infections, represent a significant public health concern in Mexico.

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