Related Experiment Video
Updated: Jun 5, 2026

Analysis of SEC-SAXS data via EFA deconvolution and Scatter
Published on: January 28, 2021
EROS: Better than SAXS!
1Center for Proteomics and Department of Pharmacology, Case Western Reserve University, Biomedical Research Building, 10900 Euclid Avenue, Cleveland, OH 44106, USA. sichun.yang@case.edu
Abstract:
Revealing the three-dimensional organization of large dynamic protein complexes in solution is challenging. To tackle this problem, Różycki and colleagues (2011) design a method combining small angle X-ray scattering (SAXS) data with the results of computer simulations. Their study offers new insights into the conformational transition induced by salt that occurs in an endosome-associated ESCRT-III CHMP3 domain.
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