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Primary multicentric cutaneous epithelioid angiosarcoma.

Murugan Sundaram1, T P Vetrichevvel, Shobana Subramanyam

  • 1Department of Dermatology and Venereology, Sri Ramachandra University, Chennai, India. murug19872@gmail.com

Indian Journal of Dermatology, Venereology and Leprology
|January 12, 2011
PubMed
Summary
This summary is machine-generated.

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Cutaneous epithelioid angiosarcoma, a rare vascular tumor, unusually presented as multicentric scalp lesions in an elderly woman. The case highlights scalp angiosarcoma with liver metastases, emphasizing atypical presentations of this malignancy.

Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • Cutaneous epithelioid angiosarcoma (CEA) is a rare vascular neoplasm.
  • Typically affects elderly men and commonly occurs on the extremities.

Observation:

  • An 81-year-old female presented with ulcerated plaques on the right temporal and parietal scalp.
  • Enlarged, tender lymph nodes in the right submaxillary and submandibular regions were noted.
  • Imaging revealed scalp soft tissue swelling and liver hyperechoic areas suggestive of metastases.

Findings:

  • Histopathology confirmed atypical epithelioid cells with high mitotic activity in the dermis and subcutis.
  • Immunohistochemistry showed positivity for CD-31, CD-33, CD-34, and vimentin, with negative cytokeratin.
  • Diagnosis of epithelioid angiosarcoma was confirmed.

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Implications:

  • This case underscores the unusual occurrence of multicentric CEA on the scalp.
  • It highlights the potential for scalp angiosarcoma to metastasize to the liver.
  • The report emphasizes the importance of considering rare presentations of vascular tumors.