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Related Experiment Video

Updated: Jun 5, 2026

Whole-Body Nanoparticle Aerosol Inhalation Exposures

Whole-Body Nanoparticle Aerosol Inhalation Exposures

Published on: May 7, 2013

Ambient air sampling during quantum-dot spray deposition.

John T Jankovic¹, Scott M Hollenbeck, Tracy L Zontek

¹Center for Nanophase Materials Sciences, UT Battelle, LLC, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA. jankovicjt@hotmail.com

International Journal of Occupational and Environmental Health

|January 13, 2011

Summary

Spray coating with quantum dots (QDs) can release nanoparticles into the air. Implementing a ventilation delay before opening enclosures effectively prevents nanoparticle release, ensuring safer air quality.

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Area of Science:

Nanotechnology
Environmental Science
Industrial Hygiene

Background:

Spray coating processes, particularly with nanomaterials like quantum dots (QDs), pose potential risks of airborne particle release.
Effective industrial hygiene strategies are crucial for managing exposure risks associated with nanosize particle emissions.

Purpose of the Study:

To assess ambient air nanoparticle emissions during spot spray coating using a Sono-Tek ExactaCoat Benchtop system.
To evaluate the effectiveness of enclosure ventilation controls in mitigating the release of aerosolized quantum dots.

Main Methods:

Ambient air sampling was conducted during spray coating of cadmium selenide and gold quantum dots (QDs).
Particle size and concentration were monitored using a scanning mobility particle sizer and condensation particle counters.
Aerosol characterization involved atomic force microscopy, electron microscopy, and chemical analysis.

Main Results:

Opening the enclosure early led to a significant increase in ambient air nanoparticle concentrations.
Implementing a ventilation delay of 10 air changes (over 99.99% concentration reduction) before door opening effectively prevented measurable aerosol particle release.
Median spray droplet size ranged from 20 to 60 micrometers.

Conclusions:

Spray coating with quantum dots generates nanosize particles that can become airborne.
A timed ventilation strategy within enclosures is a highly effective control measure for preventing the release of nanoparticles during spray coating operations.
This approach significantly enhances industrial hygiene and safety when working with nanomaterials.