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Coronary Artery Ligation and Intramyocardial Injection in a Murine Model of Infarction
Published on: June 7, 2011
Tissue engineering for post-myocardial infarction ventricular remodeling
T M Kolettis1, A Vilaeti, K Dimos
1Department of Cardiology, University of Ioannina, 1 Stavrou Niarxou Avenue, 45110 Ioannina, Greece. thkolet@cc.uoi.gr
Mini Reviews in Medicinal Chemistry
|January 13, 2011
Abstract:
Myocardial tissue engineering involves the design of biomaterial scaffolds, aiming at regenerating necrotic myocardium after myocardial infarction. Biomaterials provide mechanical support to the infarct area and they can be used as vehicles for sustained and controlled local administration of cells and growth factors. Although promising results have been reported in experimental studies, many issues need to be addressed before human use.
