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A Human Fallopian Tube Model for Investigation of C. trachomatis Infections
Published on: August 11, 2012
IgA antibodies to Chlamydia trachomatis and metabolic syndrome
Luciele Sehnem1, Luiz Carlos Bodanese, Giuseppe Repetto
1Department of Nursing and Dentistry, University of Santa Cruz do Sul, Brazil. lucielesehnem@unisc.br
Abstract:
Chlamydia pneumoniae may trigger atherogenesis. Chlamydia trachomatis (CT) can also induce endothelial activation. However, its role in metabolic syndrome (METS), a proatherogenic entity, has remained unexplored. In this study the frequencies of IgA and IgG anti-CT antibodies were evaluated by immunoenzymatic assay in METS patients and healthy controls. The survey included 238 individuals (148 with METS). The mean age was 59.7 years. IgA anti-CT antibodies were found significantly more frequently in METS patients (16.9%) than in controls (5.6%) (P= 0.015). The role of such IgA response in METS should be further investigated.
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