Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Community Based Intervention01:30

Community Based Intervention

Community-based interventions in mental health represent a paradigm shift from institution-centered care to treatments embedded within the fabric of local communities. By prioritizing inclusion and leveraging existing societal structures, this approach fosters a supportive environment conducive to addressing mental health challenges while promoting individual dignity and agency.
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
Study Designs in Epidemiology01:20

Study Designs in Epidemiology

Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and case-control studies.
Strategies for Assessing and Addressing Confounding01:25

Strategies for Assessing and Addressing Confounding

Confounding is a critical issue in epidemiological studies, often leading to misleading conclusions about associations between exposures and outcomes. It occurs when the relationship between the exposure and the outcome is mixed with the effects of other factors that influence the outcome. Given that, addressing confounding is of high importance for drawing accurate inferences in research.
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
Dosage Regimens: Designs and Approaches01:28

Dosage Regimens: Designs and Approaches

Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
Operant Conditioning Intervention01:24

Operant Conditioning Intervention

Operant conditioning serves as a foundational principle in therapeutic interventions aimed at modifying maladaptive behaviors. Central to this approach is the notion that behaviors, both adaptive and maladaptive, are learned through reinforcement. By analyzing the environmental factors that reinforce problematic behaviors, clinicians can design interventions to weaken these reinforcements and replace maladaptive behaviors with healthier alternatives.
In operant conditioning, behaviors that are...
Experimental Designs01:16

Experimental Designs

An experimental design is a systematic process that allows researchers to evaluate the relationship between dependent and independent variables. There are three widely used types of experimental design - pre-experimental design, true experimental design, and quasi-experimental design. In pre-experimental design, the researcher compares the data before and after some interventions or treatments. The true-experimental design has more than one purposefully created group, a commonly measured...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Coupling between plant nitrogen and phosphorus along water and heat gradients in alpine grassland.

The Science of the total environment·2019
Same author

Association between chronic obstructive pulmonary disease and activity of daily living among oldest-old in China: based on Chinese Longitudinal Health Longevity Survey.

International journal of chronic obstructive pulmonary disease·2019
Same author

Dexmedetomidine exerts a protective effect on ischemia-reperfusion injury after hepatectomy: A prospective, randomized, controlled study.

Journal of clinical anesthesia·2019
Same author

Mechanism of a Novel Camptothecin-Deoxycholic Acid Derivate Induced Apoptosis against Human Liver Cancer HepG2 Cells and Human Colon Cancer HCT116 Cells.

Recent patents on anti-cancer drug discovery·2019
Same author

Potential role of IL-37 signaling pathway in feedback regulation of autoimmune Hashimoto thyroiditis.

Histochemistry and cell biology·2019
Same author

β-Cyclodextrin-based hollow nanoparticles with excellent adsorption performance towards organic and inorganic pollutants.

Nanoscale·2019
Same journal

[Research progress on the impact of the digital information environment on the health of children and adolescents].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2026
Same journal

[Exploration and practice of ideological and political education integration in the "One Core, Two Integrations" curriculum model for epidemiology].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2026
Same journal

[Progress in research of visualization of ideology and politics elements in curriculum and its importance for <i>Epidemiology</i> curriculum].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2026
Same journal

[Operation of WeChat official accounts of <i>Chinese Journal of Epidemiology</i>].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2026
Same journal

[Study on the risk factors of development for mild cognitive impairment to Alzheimer's disease based on the competitive risk joint model].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2026
Same journal

[Mendelian randomization study on related factors for esophageal adenocarcinoma and Barrett's esophagus].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2026
See all related articles

Related Experiment Video

Updated: Jun 5, 2026

Measuring the Functional Abilities of Children Aged 3-6 Years Old with Observational Methods and Computer Tools
11:29

Measuring the Functional Abilities of Children Aged 3-6 Years Old with Observational Methods and Computer Tools

Published on: June 20, 2020

[Development and evaluation of complex intervention].

Miao Liu1, Zhi-heng Hong, Si-yan Zhan

  • 1Department of Epidemiology and Biostatistics, Peking University Health Science Center, Beijing 100191, China.

Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi
|January 13, 2011
PubMed
Summary
This summary is machine-generated.

Complex interventions are crucial for healthcare but require careful design and evaluation. This article presents a framework for developing and assessing these interventions, including a revised Medical Research Council model.

More Related Videos

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design
07:40

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design

Published on: May 31, 2021

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
06:16

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting

Published on: June 6, 2020

Related Experiment Videos

Last Updated: Jun 5, 2026

Measuring the Functional Abilities of Children Aged 3-6 Years Old with Observational Methods and Computer Tools
11:29

Measuring the Functional Abilities of Children Aged 3-6 Years Old with Observational Methods and Computer Tools

Published on: June 20, 2020

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design
07:40

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design

Published on: May 31, 2021

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
06:16

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting

Published on: June 6, 2020

Area of Science:

  • Health Services Research
  • Intervention Science
  • Medical Research Methodology

Context:

  • Single interventions are often insufficient for complex health issues.
  • Healthcare challenges necessitate multifaceted approaches.
  • Complex interventions require rigorous design and evaluation protocols.

Purpose:

  • To introduce a framework for the design and evaluation of complex interventions.
  • To present the revised Medical Research Council (MRC) framework.
  • To illustrate the application of the framework with practical examples.

Summary:

  • The article outlines a structured approach to developing complex interventions.
  • It details the Medical Research Council's updated guidelines for intervention design.
  • Five case studies demonstrate the framework's utility in real-world health research.

Impact:

  • Provides researchers with a robust methodology for complex intervention studies.
  • Aims to improve the quality and effectiveness of healthcare interventions.
  • Facilitates better understanding and application of intervention science principles.