[Pseudo-Meigs' syndrome caused by ovarium metastasis from colorectal cancer]

Pseudo-Meigs' syndrome caused by ovarian metastasis from colorectal cancer is extremely rare. The clinical symptoms of pleural effusion and ascites that are characteristics of pseudo-Meigs' syndrome are quite similar to those of terminal-stage colon cancer. Therefore, recognizing the clinical characteristics of pseudo-Meigs' syndrome is important. We investigated the prognosis and clinicopathological factors including age, location of the primary cancer, histology, wall depth, curative degree, synchronous/metachronous, unilateral/bilateral, lymph node metastasis, peritoneal dissemination, serum CEA level, venous invasion, and lymphatic invasion, in 5 cases of pseudo-Meigs' syndrome (PM group) and compared these findings with those of 10 cases with ovarian metastasis from colorectal cancer (control group) without pseudo-Meigs' syndrome. No significant differences were found between the PM group and the control group. The three-year survival rate was 37.5% in the PM group and 10% in the control group (logrank test, p=0.19). In the present study, no significant differences in any of the clinicopathological factors examined in this study were seen between the PM and control groups. However, we found that the surgical resection of ovarian metastasis in patients with pseudo-Meigs' syndrome improved the prognosis, similar to the situation for ovarian metastasis from colorectal cancer.