Related Experiment Video
Updated: Jun 5, 2026

Ex Vivo Treatment Response of Primary Tumors and/or Associated Metastases for Preclinical and Clinical Development of Therapeutics
Published on: October 2, 2014
[A successful case of the super elderly breast cancer patient treated with exemestane]
Katsuhisa Enomoto1, Kenichi Sakurai, Sadao Amano
1Division of Breast and Endocrine Surgery, Dept. of Surgery, Nihon University School of Medicine.
Abstract:
A case was a 91-year-old woman. The left breast lump was pointed out in April 2006. The patient was referred to a close medical examination. Mammography and breast echography showed irregular and internal heterogeneic mass tumor about 3 × 4 cm in size at the left breast CA area. We performed a needle biopsy, and it was solid-tubur carcinoma, ER (+), PgR (+), HER2 score 1+. An overall examination did not show a distant metastasis. We opted for exemestane (25 mg/day, po) because we thought that surgery was not effective with the consideration of her age and dementia. After 4 years of giving exemestane, there were no sign of apparent mass on the palpation by echography. We also did not see a side effect. No recurrence was observed under the current medical treatment. There has been a tendency to increase in breast cancer morbidity of elderly patients due to advancement in medical technology. As our experience suggested, active hormonal therapy was effective for prognosis if a patient has a hormonal sensitivity.
Related Concept Videos
Treatment Resistant Cancers
Treatment Resistent Cancers
Targeted Cancer Therapies
There are several types of targeted therapies against specific...
Cancer Survival Analysis