Related Experiment Video
Updated: Jun 5, 2026

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
Published on: June 6, 2025
[The treatment of depression in adolescents, a multi-layered challenge]
1Belgische School voor Psychoanalyse en van de Vlaamse Vereniging voor Psychoanalytische Therapie, Meulebeke, Belgium. leen.vancompernolle@telenet.be
Background:
It is generally accepted that the clinical-psychotherapeutic treatment of severely depressed adolescents is a difficult and complicated undertaking.
Aim:
To gain insight into the various factors, often present simultaneously, which block or undermine the adolescent development phase of separation-individuation and lead to depression, and to find out how the situation can be remedied.
Method:
The multi-layered hypothesis is developed with the help of case-material and takes exogenous as well as endogenous factors into account.
Results:
The investigation has demonstrated that in the treatment of depressed adolescents every possible factor needs to be taken into account if a long-lasting result is to be achieved.
Conclusion:
This result is not surprising in view of the crucial developmental stage involved which is focused on the formation of identity. This developmental process cannot be consolidated until all the necessary elements have fallen into place.
Related Concept Videos
Depression: Overview
Treatment Strategies for Psychological Disorders
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Antidepressant Drugs: MAOIs and Other Agents
Depressive Disorders: MDD and Dysthymia
Drug Therapy
Antianxiety Medications