Related Experiment Video
Updated: Jun 5, 2026

Identification of Pre-weanling 7-Day-Old Mice with Pinna Edge Biopsies
Published on: May 23, 2025
An unusual myofibroblastic proliferation of the pinna
C Rowan1, A Farboud, J Mitchard
1Faculty of Medical Sciences, University of Bristol, Bath, UK.
Introduction:
Myofibrosis of the ear is rare. Myofibromas are mesenchymal tumours which usually present in infancy but have been reported sporadically in adults.
Objective:
To present a rare case of trauma as a cause of pinnal myofibrosis.
Design And Method:
Case report. A 29-year-old soldier suffered repeated trauma from helmet wear and sports, and presented to our clinic with an exquisitely painful lump in the anti-helix of the pinna.
Results:
The lump was excised uneventfully. Pathology revealed a reactive myofibroblastic proliferation which, given the history of trauma, raised the possibility of a florid cellular repair process. The main differential diagnosis was myofibroma. Immunohistochemistry was used to exclude other possible causes.
Conclusion:
No similar case has previously been reported. The aetiology of myofibroma is unclear, but repeated trauma may be a trigger. Histological and immunohistochemical analysis are recommended when the diagnosis is ambivalent.
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