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The evolution of ferredoxins.

J Meyer1

  • 1DRF-LBio-Biochimie Microbienne CENG, 38041 Grenoble, Cedex, France.

Trends in Ecology & Evolution
|January 14, 2011
PubMed
Summary
This summary is machine-generated.

Ferredoxins, early redox proteins, are crucial evolutionary markers. Evidence suggests they originated independently at least five times, challenging common ancestry theories.

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Area of Science:

  • Biochemistry
  • Evolutionary Biology
  • Molecular Biology

Background:

  • Ferredoxins are ubiquitous electron carrier proteins containing nonheme iron and inorganic sulfur.
  • They are considered among the earliest redox proteins, vital in primitive organisms.
  • Nearly a hundred ferredoxin primary structures have been determined, aiding evolutionary studies.

Purpose of the Study:

  • To investigate the evolutionary origins of ferredoxins.
  • To determine if ferredoxins share a common ancestor or evolved independently.
  • To clarify the role of ferredoxins as evolutionary markers.

Main Methods:

  • Analysis of amino acid sequences of various ferredoxins.
  • Construction of phylogenetic trees for bacteria and oxygenic photosynthetic organisms.
  • Comparison of ferredoxin families to identify evolutionary relationships.

Main Results:

  • Most ferredoxins fall into two distinct phylogenetic groups associated with bacteria and oxygenic photosynthetic organisms.
  • Several ferredoxins appear unrelated to these major families.
  • Evidence indicates ferredoxins may belong to at least five independent phyletic lines.

Conclusions:

  • The evolutionary origin of ferredoxins is complex, with evidence supporting multiple independent origins.
  • Ferredoxins may not all descend from a single common ancestor.
  • Ferredoxins represent diverse evolutionary trajectories in biological history.