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Vitamin E levels in premenstrual syndrome
C J Chuong1, E B Dawson, E R Smith
1Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston.
American Journal of Obstetrics and Gynecology
|November 1, 1990
Summary
Peripheral vitamin E levels did not differ significantly between women with premenstrual syndrome and controls. This study found no evidence of vitamin E deficiency in premenstrual syndrome patients.
Area of Science:
- Biochemistry
- Endocrinology
- Women's Health
Background:
- Premenstrual syndrome (PMS) is a common condition affecting women's health.
- The role of micronutrients, such as vitamin E, in PMS is not fully understood.
- Previous research suggests potential links between vitamin E and PMS symptoms.
Purpose of the Study:
- To investigate the association between peripheral vitamin E levels and premenstrual syndrome.
- To compare vitamin E concentrations during different menstrual cycle phases in women with and without PMS.
Main Methods:
- A case-control study involving 10 patients with PMS and 10 healthy controls.
- Blood samples were collected every 2-3 days over three menstrual cycles.
- Vitamin E levels were quantified using fluorometry, and luteinizing hormone was measured via radioimmunoassay.
Main Results:
- No significant differences in peripheral vitamin E levels were observed between the PMS group and the control group.
- Vitamin E levels remained stable throughout the menstrual cycle in both groups.
- No significant variations were found between luteal and follicular phases within or between groups.
Conclusions:
- Peripheral vitamin E levels do not appear to be significantly altered in women with premenstrual syndrome.
- The study did not find evidence to support vitamin E deficiency as a contributing factor to PMS based on peripheral levels.
- Further research may be needed to explore other potential roles of vitamin E or different measurement methods.