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Updated: Jun 5, 2026
Deep Brain Stimulation with Simultaneous fMRI in Rodents
Published on: February 15, 2014
A novel approach to investigate neuronal network activity patterns affected by deep brain stimulation in rats
Julia Klein1, Maria L Soto-Montenegro, Javier Pascau
1Department of Psychiatry and Psychotherapy, University Medicine Berlin, Charité Campus Mitte, Berlin, Germany.
Abstract:
The establishment of new therapeutic indications for deep brain stimulation (DBS) is ambitiously promoted though the underlying mechanisms remain contested. Here, we report that PET-imaging and subsequent c-Fos-immunostaining in rats constitute a new translational approach to further understand DBS-mechanisms and -effectiveness.
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