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Related Concept Videos

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Cholesterol: Significance and Regulation

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Related Experiment Video

Updated: Jun 5, 2026

Cholesterol Efflux Assay
07:54

Cholesterol Efflux Assay

Published on: March 6, 2012

Detecting Elevated Cholesterol Levels: Part 2: Prevalence and feasibility considerations.

H L Reimer, R W Elford, S Shumak

    Canadian Family Physician Medecin De Famille Canadien
    |January 14, 2011
    PubMed
    Summary
    This summary is machine-generated.

    Physicians

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    Cholesterol Efflux Assay
    07:54

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    Published on: March 6, 2012

    High-Density Lipoprotein-Specific Phospholipid Efflux Assay
    07:08

    High-Density Lipoprotein-Specific Phospholipid Efflux Assay

    Published on: September 30, 2025

    Area of Science:

    • Clinical Chemistry
    • Cardiovascular Disease Risk Assessment

    Background:

    • Elevated cholesterol is a significant risk factor for cardiovascular disease.
    • Accurate case-finding for high cholesterol is crucial in primary care settings.

    Purpose of the Study:

    • To evaluate the Reflotron dry chemistry reflectance photometer as a tool for identifying patients with elevated cholesterol in physician offices.
    • To assess the accuracy of physicians' clinical risk factor assessments in predicting high cholesterol levels.

    Main Methods:

    • A study involving 713 adult patients in physicians' offices.
    • Determination of patient risk factor profiles.
    • Fingerprick blood cholesterol measurements using the Reflotron photometer.

    Main Results:

    • Cholesterol levels were categorized: <5.2 mmol/L (51%), 5.2-6.1 mmol/L (28%), and ≥6.2 mmol/L (21%).
    • Physicians' predictions of elevated cholesterol based on risk factors were found to be inaccurate.

    Conclusions:

    • The Reflotron photometer shows potential for cholesterol screening in primary care.
    • Clinical risk factor assessment alone is insufficient for accurately identifying patients with elevated cholesterol.