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Updated: Jun 5, 2026

Using Eggs from Schistosoma mansoni as an In vivo Model of Helminth-induced Lung Inflammation
Published on: June 5, 2012
Schistosoma mansoni infection: an immune complex disease presenting with polyarthritis
Aline Tamires Lapa1, Simone Appenzeller, Manoel B Bértolo
1Rheumatology Unit, Department of Medicine, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil.
Abstract:
Schistosomiasis or bilharzia is a parasitic disease found in tropical countries. Most infections are subclinical but may progress to chronic form characterized most frequently by the presence of liver involvement and portal hypertension. We report a patient that presented chronic polyarthritis with positive rheumatoid factor. During investigation, increased liver enzymes, negative hepatitis serologies and signs of portal hypertension on an ultrasound examination raised suspicion of S. mansoni infection. We will discuss pathophysiology and clinical manifestations of S. mansoni infection with special attention to articular involvement.
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