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[Reflex nature of the initial component of thermogenesis]
Abstract:
In experiments on dogs with sham feeding it has been shown that the initial component of thermogenesis induced by food is of reflectory nature. During sham feeding 100 g of meat after 10-15 min induced 1.2-2-fold increase of oxygen consumption as compared to the initial value. Other food products (bread, butter, glucose solution) in the same time interval produce a slightly lower but always distinct effect. Even aspartam (28 mg in 50 ml of water) induces a manifest increase of oxygen consumption. This effect is completely eliminated by atropine. alpha- and beta-adrenoblockers (combined phentolamine and propranolol hydrochloride) lead to a sharp decrease in the intensity and duration of the effect. It has been concluded that both cholinergic and adrenergic nervous routes participate in this reflectory action. A suggestion has been made that the importance of this reflex lies in the anticipating stimulation of certain metabolic processes associated with impending assimilation of the ++consumed food.
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