Transport of resistance through a long microfluidic channel

We introduce a continuous analytical model of propagation of resistance in pressure-driven flow of two-phase fluid in a single channel. This model can be used to predict and interpret experimental results in droplet microfluidics where the hydrodynamic resistance of a capillary comprises a constant part, specific to the channel and the viscosity of the continuous fluid, and a variable part, related to the presence and distribution of droplets. The continuous model is a convenient generalization of the discrete models as demonstrated via comparisons with discrete simulations and with experiments.