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Is vitamin D necessary for skeletal integrity in the elderly?
S P Thompson1, T J Wilton, D J Hosking
1Department of Biochemistry, University Hospital, Queen's Medical Centre, Nottingham, England.
Abstract:
Serum 1.25 dihydroxyvitamin D concentrations were reduced in elderly patients with femoral neck fractures, irrespective of the presence of osteomalacia. This reduction was not attributable to a decrease in vitamin D binding protein. The low rate of bone turnover in these elderly patients might reduce the requirement for vitamin D and protect against the development of osteomalacia. Serum vitamin D metabolite concentration cannot be used as a screening test for osteomalacia in these patients.
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