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Related Concept Videos

Parentral Nutrition: Centeral and Peripheral Parental Nutrition01:27

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Bioavailability Study Design: Healthy Subjects Versus Patients01:15

Bioavailability Study Design: Healthy Subjects Versus Patients

Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
Bioavailability Study Design: Single Versus Multiple Dose Studies01:11

Bioavailability Study Design: Single Versus Multiple Dose Studies

Bioavailability studies are essential for understanding how a drug is absorbed, distributed, metabolized, and excreted in the body. These studies assess the extent and rate at which the active pharmaceutical agent becomes available at the site of action. The design of bioavailability studies can involve single-dose or multiple-dose regimens, each with distinct advantages and limitations.Single-dose studies are the preferred approach due to their simplicity and reduced drug exposure for...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
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Bioequivalence Experimental Study Designs: Completely Randomized and Randomized Block Designs01:20

Bioequivalence Experimental Study Designs: Completely Randomized and Randomized Block Designs

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Clinical Trials: Overview01:11

Clinical Trials: Overview

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Related Experiment Video

Updated: Jun 5, 2026

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
04:53

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition

Published on: September 20, 2019

Complementary feeding: a Global Network cluster randomized controlled trial.

Nancy F Krebs1, K Michael Hambidge, Manolo Mazariegos

  • 1University of Colorado Denver, Aurora, CO, USA. nancy.krebs@ucdenver.edu

BMC Pediatrics
|January 15, 2011
PubMed
Summary

Daily beef supplementation in young children improved linear growth compared to fortified cereal. This study provides evidence for enhancing meat as a complementary food to reduce child mortality in low-resource settings.

Related Experiment Videos

Last Updated: Jun 5, 2026

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
04:53

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition

Published on: September 20, 2019

Area of Science:

  • Child Nutrition
  • Public Health Interventions
  • Growth Monitoring

Background:

  • Inadequate complementary feeding contributes to high child morbidity and mortality in low-resource settings.
  • Animal source foods are crucial for micronutrient intake in young children.
  • The effectiveness of regular meat consumption as a complementary food has not been systematically evaluated.

Purpose of the Study:

  • To test the hypothesis that daily beef intake improves linear growth velocity in young children.
  • To compare the efficacy of beef supplementation versus a micronutrient-fortified rice-soy cereal.
  • To evaluate the impact of complementary feeding interventions on child health outcomes.

Main Methods:

  • Cluster randomized efficacy trial conducted across four countries (Guatemala, Pakistan, DRC, Zambia).
  • 12-month daily supplementation (beef vs. fortified cereal) initiated at 6 months of age.
  • Outcome measures included anthropometry, dietary intake, biomarkers, neurocognitive development, and infectious morbidity.

Main Results:

  • Daily beef intake resulted in greater linear growth velocity compared to the fortified cereal supplement.
  • The study assessed various indicators of child development and health status.
  • Detailed findings on micronutrient status and cognitive development were collected.

Conclusions:

  • Daily meat consumption commencing at 6 months of age is efficacious in improving linear growth in young children.
  • Findings support global efforts to increase local meat availability for complementary feeding.
  • This intervention holds potential for reducing child mortality in resource-limited areas.