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Related Concept Videos

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Pharmacogenomics: Identification of New Drug Targets

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Targeted Cancer Therapies

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EPS and iPS Cells in Disease Research01:21

EPS and iPS Cells in Disease Research

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Related Experiment Video

Updated: Jun 5, 2026

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)
07:02

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)

Published on: September 14, 2010

Kawasaki disease Recent advances.

J C Burns1, T Matsubara

  • 1Jane C. Burns and Tomoya Matsubara are at the Department of Pediatrics, University of California-San Diego, La Jolla, CA 92093-0609, USA.

Trends in Cardiovascular Medicine
|January 15, 2011
PubMed
Summary

Kawasaki disease (KD) is a leading cause of acquired heart disease in children. Its cause and long-term effects on coronary arteries remain largely unknown, despite extensive research.

Area of Science:

  • Pediatrics
  • Cardiology
  • Immunology

Background:

  • Kawasaki disease (KD) is the most frequent cause of acquired heart disease in pediatric populations in the US and Japan.
  • Despite decades of research, the etiology of KD remains elusive.
  • The long-term cardiovascular consequences of KD in adulthood are not well understood.

Purpose of the Study:

  • To review the current understanding of Kawasaki disease pathogenesis.
  • To summarize advancements in the treatment of Kawasaki disease.
  • To highlight the unknown aspects of KD, including its etiology and long-term effects.

Main Methods:

  • Literature review of studies on Kawasaki disease.
  • Analysis of research progress in understanding KD pathogenesis and treatment.

Related Experiment Videos

Last Updated: Jun 5, 2026

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)
07:02

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)

Published on: September 14, 2010

  • Synthesis of existing knowledge on the epidemiology and clinical manifestations of KD.

    • Main Results:

    • Kawasaki disease is a significant pediatric health concern with unknown origins.
    • Current research has not identified the definitive cause of KD.
    • Long-term outcomes for individuals who had KD as children are still under investigation.

    Conclusions:

    • Further research is crucial to elucidate the etiology of Kawasaki disease.
    • Understanding the long-term impact of KD on coronary artery health is essential.
    • Continued investigation into pathogenesis and treatment is needed for this mysterious illness.