Related Experiment Video
Updated: Jun 5, 2026

Generation of Human Induced Pluripotent Stem Cells from Peripheral Blood Using the STEMCCA Lentiviral Vector
Published on: October 31, 2012
The challenges and promises of blood engineered from human pluripotent stem cells
Gautam G Dravid1, Gay M Crooks
1Department of Pathology and Laboratory Medicine, Department of Pediatrics, Broad Stem Cell Research Center, University of California Los Angeles (UCLA), David Geffen School of Medicine, 610 Charles E Young Drive East, Los Angeles, CA 90095-1732, USA. gdravid@mednet.ucla.edu
Abstract:
The concept that stem cells can be used to replace and regenerate tissue was founded over half a century ago using hematopoietic stem cells in the clinical field of bone marrow transplantation. The development of human embryonic stem cell lines and patient-specific induced pluripotent stem cells has the potential to overcome the problem presented by shortages of immunologically compatible hematopoietic stem cell donors. This review summarizes the current advances made and limitations to be overcome in order to realize the full potential of engineering blood from pluripotent stem cells for clinical use.
Related Concept Videos
Induced Pluripotent Stem Cells
Somatic cells are...
Induced Pluripotent Stem Cells
Induced Pluripotent Stem Cells
Stem Cell Culture
Embryonic Stem Cells
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
Embryonic Stem Cells
