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Updated: Jun 5, 2026

Functional Interrogation of Adult Hypothalamic Neurogenesis with Focal Radiological Inhibition
Published on: November 14, 2013
Short photoperiods alter cannabinoid receptor expression in hypothalamic nuclei related to energy balance
Zachary M Weil1, Joanna L Workman, Kate Karelina
1Department of Neuroscience, Ohio State University, Columbus, OH 43210, USA. zachary.weil@osumc.edu
Abstract:
This study examined the photoperiodic regulation of energy balance and cannabinoid receptor expression in the Siberian hamster (Phodopus sungorus) hypothalamus. Short day lengths, beginning at weaning, reduced food intake, body mass and fat pad masses and also decreased cannabinoid receptor immunostaining in the anterior and lateral hypothalamic nuclei of male hamsters. These data suggest a potential role for reduced cannabinoid drive in mediating short day-induced alterations in energy balance.
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