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Updated: Jun 5, 2026

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice
Published on: February 18, 2015
Oral candidiasis mimicking tongue cancer
Tomohisa Shibata1, Daisuke Yamashita, Shingo Hasegawa
1Department of Otolaryngology-Head and Neck Surgery, Kobe University Hospital, Japan. tshibata-kob@umin.ac.jp
Abstract:
Candida species inhabit the mucosal surfaces of healthy individuals. Major forms of oral candidiasis are pseudomembranous and atrophic form, but chronic hyperplastic candidiasis (CHC) is rarely seen. We encountered a nodule caused by candidal infection on a forearm flap in the oral cavity mimicking a recurrent tongue cancer, which revealed as CHC by histopathological examination. Like other forms of oral candidiasis, the nodule well responded to the treatment of antifungal agents and eventually disappeared. When an intraoral nodule is observed, the possibility of CHC should be taken into consideration.
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