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Related Concept Videos

Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
Encephalitis ll: Pathophysiology01:26

Encephalitis ll: Pathophysiology

Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
Rabies01:28

Rabies

Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...

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Powassan encephalitis in new brunswick.

W M Fitch, H Artsob

    Canadian Family Physician Medecin De Famille Canadien
    |January 15, 2011
    PubMed
    Summary

    This report details a case of Powassan encephalitis in New Brunswick, Canada. The patient recovered significantly but experienced minor memory loss, highlighting the importance of recognizing this rare viral encephalitis.

    Area of Science:

    • Neurology
    • Infectious Diseases
    • Public Health

    Background:

    • Powassan encephalitis is a rare, tick-borne viral illness affecting the central nervous system.
    • Cases are infrequently reported, with limited geographic distribution noted in Canada.

    Purpose of the Study:

    • To report the first case of Powassan encephalitis diagnosed in New Brunswick, Canada.
    • To describe the clinical presentation, diagnostic considerations, and patient outcome.

    Main Methods:

    • Case report of a 76-year-old male patient diagnosed with viral encephalitis.
    • Clinical assessment and follow-up of cognitive and physical functioning.

    Main Results:

    • The patient was diagnosed with Powassan encephalitis following a stay in Upper Rexton, New Brunswick.

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  • Seven months post-onset, significant improvement in cognitive and physical function was observed, with residual minor memory impairment.
  • This represents the 11th recognized case in Canada and the first documented case in New Brunswick.
  • Conclusions:

    • Powassan encephalitis can occur in New Brunswick, underscoring the need for increased awareness among clinicians.
    • Early recognition and management are crucial for patient recovery, though long-term sequelae like memory impairment may persist.