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Related Concept Videos

Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
Knee Joint01:23

Knee Joint

The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris group...
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...

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Related Experiment Video

Updated: Jun 5, 2026

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
06:06

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint

Published on: July 22, 2021

Update on osteoarthritis.

I K Tsang

    Canadian Family Physician Medecin De Famille Canadien
    |January 15, 2011
    PubMed
    Summary
    This summary is machine-generated.

    Osteoarthritis, the most common arthritis, has recognized clinical features but poorly understood causes. Management focuses on education, physical therapy, medication, and surgery for symptom relief and function restoration.

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    Fu's Subcutaneous Needling for Knee Osteoarthritis Pain
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    Fu's Subcutaneous Needling for Knee Osteoarthritis Pain

    Published on: March 24, 2023

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    Last Updated: Jun 5, 2026

    Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
    06:06

    Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint

    Published on: July 22, 2021

    Fu's Subcutaneous Needling for Knee Osteoarthritis Pain
    07:19

    Fu's Subcutaneous Needling for Knee Osteoarthritis Pain

    Published on: March 24, 2023

    Area of Science:

    • Rheumatology
    • Orthopedics

    Background:

    • Osteoarthritis (OA) is the predominant form of arthritis in humans.
    • Clinical presentation and diagnosis of OA are well-established.
    • The underlying etiopathogenesis of osteoarthritis remains largely unclear.

    Purpose of the Study:

    • To outline the current understanding of osteoarthritis.
    • To highlight recent advancements in OA definition and classification.
    • To present a comprehensive management strategy for OA.

    Main Methods:

    • Review of clinical features and diagnostic criteria for osteoarthritis.
    • Analysis of recent consensus reports on OA definition and classification.
    • Outline of a four-fold management approach: educational, physiatric, medical, and surgical.

    Main Results:

    • Established clinical recognition and diagnostic ease of osteoarthritis.
    • Recent formal definition and classification by expert workshops.
    • A multi-faceted management strategy is recommended.

    Conclusions:

    • Osteoarthritis is a common condition with clear clinical recognition.
    • Standardized definitions and classifications are now available.
    • Individualized, multi-modal management is crucial for symptomatic relief and functional recovery in OA patients.