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Updated: Jun 5, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
Treatment challenges in pediatric stroke patients
1Department of Pediatric Neurology, School of Medicine, Ankara University, Turkey.
Insights
This 18-year study on pediatric stroke found that appropriate prophylactic treatment for children with stroke, particularly those with multiple risk factors, significantly reduces recurrence rates.
Area of Science:
- Pediatric Neurology
- Cerebrovascular Diseases
Background:
- Stroke in children is a significant concern with various etiologies.
- Understanding risk factors and treatment efficacy is crucial for improving outcomes.
Purpose of the Study:
- To analyze 18 years of experience with pediatric stroke.
- To evaluate the impact of prophylactic treatment on stroke recurrence.
Main Methods:
- Retrospective analysis of 108 pediatric patients diagnosed with arterial ischemic stroke or sinovenous thrombosis.
- Patients were followed for a mean period of 4.9 years.
Main Results:
- Multiple risk factors were identified in 44 patients.
- Recurrence occurred in only three patients.
- Prophylactic treatment was administered to 17 patients, predominantly those with multiple risk factors (P = .024).
Conclusions:
- Targeted prophylactic treatment in pediatric stroke patients is effective in reducing recurrence.
- Identifying and managing risk factors is essential for preventing recurrent stroke events.
Abstract:
Aim. In this study we presented our experience of 18 years on the etiology, risk factors, prophylactic and acute treatment, the effect of treatment to recurrence rate of patients with stroke. Methods. The population included 108 patients who had been treated for stroke at Pediatric Neurology Department of Ankara University with the diagnosis of arterial ischemic stroke and sinovenous thrombosis between January 1992 and August 2010. Forty-one girls (38%) and 67 boys (62%) with mean symptom age 3.1 ± 4.04 years, (0-18 years old) were followed up with a mean period of 4.9 ± 3.78 years (0-17 years). Results. 30 patients had no risk factors, 34 patients had only one risk factor and 44 patients had multiple risk factors. Recurrence was seen in three patients. There was no any statistical correlation between the recurrence of stroke and the existence of risk factors (P = .961). Seventeen patients received prophylactic treatment; 2 of them without any risk factors, 3 had one risk factor, 12 patients, who constituted the majority of our patients, had multiple risk factors (P = .024). Conclusion. With this study we showed that the right prophylaxis for right patients reduces the rate of recurrence.
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