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Updated: Aug 17, 2026

Generalized Psychophysiological Interaction (PPI) Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
Published on: November 14, 2017
[P300 and dementia: diagnostic relevance. I]
U Wranek1, G Ladurner, W Klimesch
1Institut für Psychologie, Universität und Abteilung für Neurologie der Landesnervenklinik, Salzburg.
Abstract:
Visual evoked potentials, including the P300 response, and reaction time were recorded from 20 patients with multi-infarct dementia, 20 nondemented patients with brain-infarct diseases, and 20 age-matched control subjects. Additionally the patients were assessed using the WAIS-index. Prolonged P300 latency and reaction time occurred in both of the patient-groups, correlated significantly with the WAIS-index. However, effects regarding to P300 latency and reaction time were not strong enough to allow individual classifications.
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