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Single Molecule Analysis of Laser Localized Psoralen Adducts
Published on: April 20, 2017
A water-soluble C60-porphyrin compound for highly efficient DNA photocleavage
Cuisong Zhou1, Qiaolin Liu, Wei Xu
1College of Chemistry, Sichuan University, Chengdu, China. zcs@scu.edu.cn
Chemical Communications (Cambridge, England)
|January 15, 2011
Abstract:
A water-soluble covalently linked C(60)-porphyrin compound-C(60)Por is reported to show enhanced DNA-cleaving activity. The highly enhanced DNA-cleaving activity is expected to be ascribed to the high water-solubility and affinity of C(60)Por to DNA, as well as to the accessibility to the charge-separated states C(60)˙(-)-Por˙(+) formed under radiation.
