Related Experiment Video
Updated: Jun 5, 2026
12:28
Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
Published on: June 3, 2020
Biogerontology in Turkey: a brief report
Yesim Kutsal1, Ceyda Kabaroglu, Dilek Aslan
1Department of PMR, Hacettepe University Faculty of Medicine, Ankara, Turkey. ygkutsal@gmail.com
Biogerontology
|January 15, 2011
Summary
Biogerontology research in Turkey primarily targets slowing the aging process, focusing on caloric restriction and oxidative stress. Future studies require increased resources and scientific collaboration for advancements in aging research.
Area of Science:
- Biogerontology
- Aging Research
Background:
- Biogerontology in Turkey has concentrated on retarding the aging process.
- Key areas of focus include caloric restriction and oxidative stress mechanisms.
Purpose of the Study:
- To review the current state of biogerontology in Turkey.
- To provide recommendations for future research directions.
Main Methods:
- Literature review of Turkish scientific publications on biogerontology.
- Analysis of prevalent research themes and methodologies.
Main Results:
- Turkish biogerontology research predominantly investigates oxidant and anti-oxidant systems in various tissues.
- The field shows a focus on general aging process retardation.
Conclusions:
- Significant need for enhanced manpower, funding, and infrastructure in Turkish biogerontology.
- Recommendations for future studies to address resource limitations and foster growth.
Related Concept Videos
01:27Pharmacodynamics in Geriatric Patients: Effects of Age
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
01:00Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are not...
01:22Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption
As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
01:18Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism
Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
01:19The Effect of Aging on Tissues
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
01:15Drug Dosing: Geriatric Patients
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...