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Published on: November 6, 2020
Intravenous fluconazole for bilateral endogenous Candida endophthalmitis.
Thirupathy Annamalai1, Kenneth Choong Sian Fong, May May Choo
1Department of Ophthalmology, University of Malaya, Kuala Lumpur, Malaysia. thirusukan@yahoo.com
Summary
This case study highlights successful treatment of endogenous fungal endophthalmitis using intravenous fluconazole. Early suspicion and prompt treatment are crucial for managing this severe ocular infection, especially in diabetic patients.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Mycology
Background:
- Endogenous endophthalmitis is a severe intraocular infection.
- Fungal endophthalmitis requires prompt diagnosis and treatment.
- Diabetes mellitus is a risk factor for endogenous fungal endophthalmitis.
Observation:
- A 54-year-old male with poorly controlled diabetes presented with bilateral vision loss and eye pain.
- Ocular examination revealed signs of vitritis, hypopyon, and white opacities.
- Diagnosis of bilateral endogenous endophthalmitis was made.
Findings:
- Vitreous cultures confirmed Candida albicans infection, sensitive to fluconazole.
- Intravenous fluconazole treatment led to complete resolution of endophthalmitis.
- Patient's vision improved significantly to 6/12 in both eyes.
Implications:
- High index of suspicion for fungal endophthalmitis is necessary in immunocompromised patients.
- Intravenous fluconazole is an effective treatment for Candida endophthalmitis.
- Prompt management can prevent vision loss in endogenous endophthalmitis.
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