Related Experiment Video
Updated: Jun 5, 2026

Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
Dentists' knowledge about anaphylaxis caused by local anaesthetics
F Çetinkaya1, G Sezgin, O Mert Aslan
1Department of Pediatrics and Pediatric Allergy, Maltepe University School of Medicine, Istanbul, Turkey. feyzulkaya@gmail.com
Dentists demonstrate inadequate knowledge of anaphylaxis symptoms, signs, and management, posing a risk to patient safety. Urgent educational programs are needed to improve their understanding of local anesthetic allergy and anaphylaxis.
Area of Science:
- Dental Anesthesiology
- Allergy and Immunology
- Emergency Medicine
Background:
- IgE-mediated systemic reactions to local anesthetics, though rare, can occur in dental practice.
- Dentists' familiarity with anaphylaxis symptoms, signs, and management is not well-established.
Purpose of the Study:
- To evaluate the knowledge of dentists regarding the symptoms, signs, and current treatment of anaphylaxis.
- To identify gaps in dental professionals' understanding of managing anaphylactic reactions.
Main Methods:
- An anonymous questionnaire with 15 questions was administered to dentists in Istanbul.
- The study surveyed dentists working in private practices to assess their knowledge of anaphylaxis.
Main Results:
- None of the 86 participating dentists were fully aware of all anaphylaxis symptoms and signs.
- Only 48.8% identified epinephrine as the first-line treatment, and 55.6% kept it in their offices.
- Just 31.5% recognized the intramuscular route as the most effective for epinephrine administration.
Conclusions:
- Dentists' knowledge of local anesthetic allergy and anaphylaxis is insufficient, potentially endangering patient lives.
- There is an urgent need for educational programs to enhance dentists' understanding and management of anaphylaxis.
More Related Videos
08:49Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention
Published on: October 16, 2013
05:43Topical Airway Anesthesia for Awake-endoscopic Intubation Using the Spray-as-you-go Technique with High Oxygen Flow
Published on: January 13, 2017
Related Concept Videos
Local Anesthetics: Adverse Effects
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Allergic Reactions: Anaphylaxis
Local Anesthetics: Pharmacokinetics
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Local Anesthetics: Chemistry and Structure-Activity Relationship
Local Anesthetics: Clinical Application as Spinal Anesthesia