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Fungal malignant external otitis.

Yaniv Hamzany1, Ethan Soudry, Michal Preis

  • 1Department of Otolaryngology, Head and Neck Surgery, Rabin Medical Center, Petah Tiqwa, Israel. yhamzany@gmail.com

The Journal of Infection
|January 18, 2011
PubMed
Summary
This summary is machine-generated.

Fungal malignant external otitis (MEO) is more invasive than bacterial MEO, often requiring aggressive treatment including hyperbaric oxygen therapy. Survival rates are similar for both fungal and bacterial MEO cases.

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Area of Science:

  • Infectious Diseases
  • Otolaryngology
  • Mycology

Background:

  • Malignant external otitis (MEO) is a severe infection of the external auditory canal.
  • Fungal MEO is less common but may present with distinct clinical features and outcomes compared to bacterial MEO.

Purpose of the Study:

  • To investigate the clinical characteristics and outcomes of fungal MEO.
  • To compare fungal MEO with non-fungal MEO in terms of patient demographics, clinical presentation, and treatment response.

Main Methods:

  • Retrospective review of 60 MEO patient records from 1990-2008.
  • Comparison of clinical characteristics and outcomes between fungal and non-fungal MEO groups.

Main Results:

  • Fungal MEO, primarily caused by Candida spp., was observed in 15% of patients.
  • Fungal MEO patients were younger, experienced more facial nerve palsies, and had fewer positive bacterial cultures.
  • Fungal MEO cases showed higher rates of persistent infection, required more frequent surgery, and benefited from hyperbaric oxygen therapy.

Conclusions:

  • Fungal MEO is likely a secondary complication of prolonged antibiotic treatment for bacterial MEO.
  • Fungal MEO demonstrates more invasive characteristics than bacterial MEO.
  • Aggressive treatment, including consideration of hyperbaric oxygen therapy, is recommended for fungal MEO.