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Updated: Jun 5, 2026

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
[Bipolar disorder: Continuity from child to adult?]
D Da Fonseca1, F Bat, N Rouviere
1Service de Pédopsychiatrie, bd Sainte Marguerite 13009 Marseille, France. ddafonseca@ap-hm.fr
Abstract:
Early onset (pediatric) bipolar disorders are still an issue of much controversy due to several clinical particularities of the thymic episodes at this age. To date, there is indeed no consensus regarding the prevalence of bipolar disorders before puberty. Diagnosis criteria in children and young adolescents remain thus elusive. The purpose of this review is to provide an overview of this issue. The idea of continuity, from childhood to adulthood, in bipolar disorders also raises important questions regarding predictive factors of bipolar disorders in adults. Studies on the childhood of bipolar adults, as well as studies on the children of bipolar parents will be reviewed, in an attempt to identify the psychopathological substrates of bipolar disorders.
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