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Updated: Jun 5, 2026

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
[Bipolar affective disorders: Models and assessment of psychological treatments]
M Maurel1, J-M Azorin, M Adida
1Pôle Universitaire de Psychiatrie, Hôpital S(te) Marguerite, 270 bd de S(te) Marguerite 13274 Marseille cedex 9. muriele.maurel@ap-hm.fr
Abstract:
Psychological therapies dedicated to bipolar patients have attracted major interest and many publications have been devoted to them in the last five years. The efficiency of Psychoeducation, Cognitive and behavioral therapy, Behavioral family therapy and Interpersonal and Social Rhythm Therapy, have specially been focused on. These approaches share a common background of psychoeducation and are closely linked with the transnosographical model from Zubin and Spring as well as basic behavioral and cognitive technical requirements. All these therapies focus on medication adherence, regular lifestyle, early recognition of relapse and early pharmacologic intervention. There are some differences between advantages from each approach, but the overall effect is positive in enhancing medication adherence and preventing manic relapses, and also in preventing depressive episodes and improving quality of life. These robust and corroborating results should probably be integrated in future guidelines for the management of bipolar disorders.
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