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Updated: Jun 5, 2026

Transplantation Into the Mouse Ovarian Fat Pad
Published on: September 7, 2016
Neoplastic transformation of endocervicosis into an extraovarian mucinous cystadenocarcinoma
Arnold-Jan Kruse1, Brigitte Slangen, Gerard A Dunselman
1GROW, School for Oncology and Developmental Biology, University of Maastricht/Maastricht University Medical Center, 6202AZ Maastricht, The Netherlands. arnoldjankruse@hotmail.com
Abstract:
Although extraovarian mucinous cystadenocarcinomas resemble primary ovarian carcinomas, both histologically and clinically, their specific etiology is not clear. This is the first report to show neoplastic transformation of endocervicosis into an extraovarian mucinous cystadenocarcinoma. The histologic spectrum and specific KRAS mutational analysis for this tumor were the same as for their ovarian counterparts. This supports a müllerian origin and the current approach to extrapolate the results from ovarian mucinous cystadenocarcinoma trials in prescribing treatment for patients with extraovarian mucinous cystadenocarcinomas.
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