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Updated: Jun 5, 2026

Phenotyping Mouse Pulmonary Function In Vivo with the Lung Diffusing Capacity
Published on: January 6, 2015
Reduced diffusion lung capacity in patients with type 2 diabetes mellitus predicts hospitalization for pneumonia
Oana L Klein1, Lewis J Smith, Matthew Tipping
1Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States. oklein@nmh.org
Abstract:
Among 4164 patients, those with type 2 diabetes mellitus (DM) had lower lung diffusion capacity (DLCO) compared with those without DM (DLCO mean±SE: 15.7±0.3 vs. 17.0±0.2 mL/min/mm Hg, p<0.01). Reduced DLCO predicted hospitalization for pneumonia independent of diabetes control, severity and co-morbidities (OR=2.4, CI 1.08-5.31).
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