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Treatment of endocarditis due to Proteus species: a literature review

Ankur Kalra1, Christine Cooley, Constantine Tsigrelis

  • 1Department of Medicine, Cooper University Hospital, UMDNJ-Robert Wood Johnson Medical School, 401 Haddon Ave, Camden, NJ 08103, USA. kalra-ankur@cooperhealth.edu

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
|January 18, 2011
PubMed

Insights

Proteus mirabilis endocarditis is a rare bacterial infection. This case highlights successful treatment with ampicillin and gentamicin, offering insights into managing this uncommon condition.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Microbiology

Background:

  • Endocarditis, an infection of the heart's inner lining, is typically caused by common bacteria.
  • Infections due to Proteus species, a genus of Gram-negative bacteria, are infrequently associated with endocarditis.

Observation:

  • A rare case of endocarditis caused by Proteus mirabilis is presented.
  • The patient's infection involved the heart valves, a common site for endocarditis.

Findings:

  • Successful treatment of Proteus mirabilis endocarditis was achieved using a combination of ampicillin and gentamicin.
  • A review of previously reported cases of Proteus endocarditis was conducted to analyze treatment strategies.

Implications:

  • This case contributes to the limited literature on Proteus endocarditis, emphasizing successful therapeutic options.
  • The findings suggest that ampicillin and gentamicin can be an effective regimen for treating Proteus endocarditis.
  • Further research into optimal antimicrobial strategies for rare bacterial endocarditis is warranted.

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