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A new dimeric resveratrol from the roots of Shorea roxburghii
Winitra Patcharamun1, Jirapast Sichaem, Pongpan Siripong
1Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand.
Abstract:
A new resveratrol dimer, roxburghiol A (1) together with eleven known compounds were isolated from the roots of Shorea roxburghii. Their structures were identified on the basis of spectroscopic evidence and physicochemical properties. All isolated compounds were evaluated for their cytotoxicity (KB and HeLa cells). Compounds 8 and 9 showed potent cytotoxicity against both KB and HeLa cell lines with IC(50) values of 6.5, 8.5 and 8.7, 10.1 μg/mL, respectively.
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