Development of metal complex imprinted solid-phase microextraction fiber for 2,2'-dipyridine recognition in aqueous...

Area of Science:

• Analytical Chemistry
• Materials Science
• Polymer Chemistry

Background:

• Developing selective extraction materials is crucial for trace analysis.
• Molecularly imprinted polymers (MIPs) offer tailored recognition but can be affected by solvent interactions.
• Metal complex imprinting provides a novel approach for enhanced selectivity.

Purpose of the Study:

• To develop and evaluate a novel metal complex imprinted polymer (CIP) coated solid-phase microextraction (SPME) fiber.
• To assess the recognition capability and selectivity of the CIP fiber for a specific metal complex template.
• To optimize extraction conditions and apply the method for analyzing 2,2 -dipyridine in real-world samples.

Main Methods:

• Fabrication of a CIP-coated SPME fiber targeting [Cu(OAc)(2)(2,2 -dipyridine)].
• Comparative analysis of adsorption capacity with MIP and nonimprinted polymer (NIP) fibers.
• Investigation of extraction parameters (pH, solvent, metal ions) and ligand selectivity.
• Quantification of 2,2 -dipyridine using High-Performance Liquid Chromatography with Ultraviolet detection (HPLC/UV).

Main Results:

• CIP-coated fiber exhibited significantly higher adsorption capacity (2.2-2.6 times) than MIP and NIP fibers.
• CIP demonstrated enhanced binding affinity and selectivity for 2,2 -dipyridine over structural analogues.
• The CIP coating was stable and effective in aqueous media, unlike MIP which showed reduced imprinting in protic solvents.
• HPLC/UV analysis yielded a linear range of 10-200 μg/L for 2,2 -dipyridine with a detection limit of 2.0 μg/L.
• Successful application in spiked tap water, wastewater, and urine samples with high recoveries (80.3-103.3%) and low RSDs (5.5-8.9%).

Conclusions:

• The novel CIP-coated SPME fiber offers superior recognition and adsorption capabilities for the target metal complex.
• CIP technology provides a robust and selective extraction method, overcoming limitations of traditional MIPs in aqueous environments.
• The developed method is efficient and accurate for the trace analysis of 2,2 -dipyridine in complex matrices.