Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Bacterial Meningitis I: Introduction

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...

Bacterial Meningitis

Bacterial Meningitis

Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...

Viral Meningitis

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...

Bacterial Meningitis II: Pathophysiology

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...

Brain Abscess l: Introduction

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...

Acute Pyelonephritis II: Diagnostic Studies and Management

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A multivariable probability score integrating routine immunoassay results for the immunological assessment of antisynthetase syndrome.

Frontiers in immunology·2026

Same author

Optimizing line blot assays: impact of band intensity adjustment on diagnostic performance in myositis autoantibodies testing.

Clinical rheumatology·2026

Same author

Factors associated with short-term adverse events in hypertensive acute heart failure.

Acta cardiologica·2026

Same author

Changing Patterns in Hospitalisations of Patients with Systemic Lupus Erythematosus over Three Decades at a Tertiary Referral Centre in Catalonia.

Journal of clinical medicine·2026

Same author

Evaluation of particle-based multi-analyte technology for autoantibody detection in systemic sclerosis: concordance with conventional methods and clinical associations.

Clinical and experimental rheumatology·2026

Same author

Complete clinical and serological remission of anti-synthetase syndrome after autologous haematopoietic stem cell transplantation.

Clinical and experimental rheumatology·2026

Search research articles

Related Experiment Video

Updated: Jun 5, 2026

Induction of Leptomeningeal Cells Modification Via Intracisternal Injection

Induction of Leptomeningeal Cells Modification Via Intracisternal Injection

Published on: May 7, 2020

Amoxicillin-induced acute aseptic meningitis.

Sergio Prieto-González¹, Rosa Escoda, Emmanuel Coloma

¹Department of Internal Medicine, Clinical Institute of Medicine and Dermatology, Hospital Clínic, University of Barcelona, Villarroel 170, Barcelona 08036, Spain. sprieto@clinic.ub.es

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia

|January 18, 2011

Summary

Amoxicillin can cause drug-induced aseptic meningitis, a rare but serious condition. Prompt recognition and discontinuation of the antibiotic are crucial for patient recovery.

More Related Videos

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

Published on: November 5, 2019

Related Experiment Videos

Last Updated: Jun 5, 2026

Induction of Leptomeningeal Cells Modification Via Intracisternal Injection

Induction of Leptomeningeal Cells Modification Via Intracisternal Injection

Published on: May 7, 2020

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

Published on: November 5, 2019

Area of Science:

Neurology
Pharmacology

Background:

Aseptic meningitis is a non-infectious inflammation of the meninges.
Drug-induced aseptic meningitis is a rare adverse drug reaction.
Amoxicillin is a widely prescribed antibiotic.

Observation:

A 58-year-old man developed fever and headache after amoxicillin intake.
Cerebrospinal fluid analysis revealed lymphocytic pleocytosis.
The patient had a history of two similar episodes potentially linked to amoxicillin.

Findings:

The patient's symptoms resolved after amoxicillin discontinuation and supportive care.
The case meets diagnostic criteria for drug-induced aseptic meningitis.
Recurrent episodes suggest a causal relationship with amoxicillin.

Implications:

Healthcare providers should consider amoxicillin as a potential cause of aseptic meningitis.
Awareness of this adverse drug reaction is important due to amoxicillin's common use.
Early diagnosis and antibiotic withdrawal can prevent severe complications.