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Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice
Published on: April 13, 2015
Physiologic assessment of coronary artery stenosis severity
1Department of Medicine, Cardiovascular Division, University of Minnesota, Minneapolis, MN 55455, USA.
Insights
Selective coronary arteriography is the gold standard for diagnosing coronary artery disease. Despite advances in noninvasive methods, this invasive test remains crucial for evaluating atherosclerotic lesions.
Area of Science:
- Cardiovascular Medicine
- Diagnostic Imaging
Background:
- Selective coronary arteriography has been the definitive diagnostic tool for assessing coronary atherosclerosis for over 25 years.
- Numerous noninvasive techniques have been developed to evaluate the impact of reduced coronary flow on the heart.
Purpose of the Study:
- To highlight the enduring clinical significance of selective coronary arteriography.
- To underscore its role in assessing atherosclerotic lesions in human coronary circulation.
Main Methods:
- Review of the established role and clinical practice of selective coronary arteriography.
- Comparison with the diagnostic capabilities of emerging noninvasive cardiovascular assessment techniques.
Main Results:
- Selective coronary arteriography remains the ultimate diagnostic test for coronary atherosclerosis.
- Noninvasive methods have not supplanted the diagnostic preeminence of coronary arteriography.
Conclusions:
- Coronary arteriography continues to be the gold standard for evaluating coronary artery disease.
- Its established accuracy and clinical utility ensure its continued importance in cardiology.
Abstract:
For over a quarter-century, selective coronary arteriography has remained the ultimate diagnostic test for assessing the significance of atherosclerotic lesions in the coronary circulation of humans. Despite the development of many noninvasive techniques designed to assess effects of limitations in the ability to augment coronary flow on myocardial perfusion, function, and metabolism, the coronary arteriogram has maintained its clinical position of preeminence.
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