Related Experiment Video
Updated: Jun 5, 2026

Dissection of Drosophila melanogaster Flight Muscles for Omics Approaches
Published on: October 17, 2019
Transcriptional control of muscle proteins
1Department of Cardiology, St. Elizabeth's Hospital, Tufts University School of Medicine, 736 Cambridge Street, Boston, MA 02135, USA.
Abstract:
The development of a muscle cell from a precursor cell involves a massive adjustment of gene expression such that over 50 previously silent genes are expressed to produce the muscle proteins required for contractile functions. In differentiated muscle, hormonal and physiologic stimuli modify the expression of these proteins primarily at the level of transcription. How does the cell regulate the switching on and switching off of specific genes to produce the muscle phenotype and respond to new conditions?
Related Concept Videos
Master Transcription Regulators
Master Transcription Regulators
Regulation of Expression Occurs at Multiple Steps
Transcription results in the generation of precursor (pre-mRNA) that consists of both exons and introns, which needs further processing before being translated to a...
Transcription
Transcription Can Produce Different Kinds of RNA Molecules
In eukaryotes,...
Transcription
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
Transcription Can Produce Different Kinds...
Regulation of Expression at Multiple Steps

