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Constipation and colonic transit times in children with morbid obesity
Olga H vd Baan-Slootweg1, Olivia Liem, Noor Bekkali
1Department of Pediatric Gastroenterology and Nutrition, Emma's Children's Hospital/AMC, Amsterdam, the Netherlands.
Insights
Functional constipation is common in children with morbid obesity, affecting 21%. However, most do not have delayed colonic transit times (CTTs), suggesting motility is not the primary issue.
Area of Science:
- Pediatric Gastroenterology
- Obesity Research
- Digestive Health
Background:
- Morbid obesity in children is a growing concern with potential gastrointestinal complications.
- Functional constipation is a common pediatric issue, but its prevalence in obese children is not well-defined.
Purpose of the Study:
- To determine the frequency of functional constipation in children with morbid obesity using Rome III criteria.
- To assess colonic motility in these children by measuring colonic transit times (CTTs).
Main Methods:
- Ninety-one children (ages 8-18) with morbid obesity participated in a randomized controlled obesity treatment study.
- Standardized questionnaires assessed bowel habits, and radioopaque markers measured CTTs. Food diaries were analyzed.
Main Results:
- Functional constipation was diagnosed in 21% of children according to Rome III criteria.
- Delayed CTT (>62 hours) was found in only 10.5% of constipated children and 8.3% of non-constipated children.
- No significant dietary differences (fiber, fat intake) were observed between constipated and non-constipated groups.
Conclusions:
- Functional constipation is highly prevalent in children with morbid obesity.
- Abnormal colonic motility, indicated by delayed CTT, is present in only a small subset of these children.
- Constipation in obese children does not appear to be related to fiber or fat intake.
Objectives:
The aim of the study was to determine the frequency of functional constipation according to the Rome III criteria in children with morbid obesity and to evaluate by measuring colonic transit times (CTTs) whether decreased colonic motility is present in these children.
Patients And Methods:
Ninety-one children with morbid obesity ages 8 to 18 years, entering a prospective, randomized controlled study evaluating the effect of an outpatient versus inpatient treatment program of obesity, participated. All of the children filled out a standardized questionnaire regarding their bowel habits, and CTTs were measured using radioopaque markers. Food diaries were also recorded to evaluate their diet.
Results:
A total of 19 children (21%) had functional constipation according to the Rome III criteria, whereas 1 child had functional nonretentive fecal incontinence. Total CTT exceeded 62 hours in only 10.5% of the children with constipation, and among them, 2 had a total CTT of >100 hours. In the nonconstipated group 8.3% had a delayed CTT. Furthermore, no difference was found between the diet of children with or without constipation, specifically not with respect to fiber and fat intake.
Conclusions:
Our study confirms a high frequency of functional constipation in children with obesity, using the Rome III criteria. However, abnormal colonic motility, as measured by CTT, was delayed in only a minority of patients. No relation was found between constipation in these children and fiber or fat intake.
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