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Hormonal manipulation and neonatal imprinting of carbonic anhydrase isozymes in rat liver
S Jeffery1, C A Wilson, N D Carter
1Department of Child Health, St. George's Hospital Medical School, London, United Kingdom.
Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme
|September 1, 1990
Abstract:
Thyroidectomy has a feminizing effect on the carbonic anhydrase isozymes II and III in male rat liver. These isozymes are known to be sexually differentiated but no treatment so far administered has produced total feminization and this is also true for thyroidectomy. Neonatal castration, however, does produce this result, suggesting the possibility of androgen imprinting for these isozymes during the neonatal period.